bolt-lmm_2.3.2+dfsg-3+b1_amd64.deb


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Description

bolt-lmm - Efficient large cohorts genome-wide Bayesian mixed-model association testing

Property Value
Distribution Debian 10 (Buster)
Repository Debian Main amd64
Package name bolt-lmm
Package version 2.3.2+dfsg
Package release 3+b1
Package architecture amd64
Package type deb
Installed size 925 B
Download size 323.46 KB
Official Mirror ftp.br.debian.org
The BOLT-LMM software package currently consists of two main algorithms, the
BOLT-LMM algorithm for mixed model association testing, and the BOLT-REML
algorithm for variance components analysis (i.e., partitioning of
SNP-heritability and estimation of genetic correlations).
The BOLT-LMM algorithm computes statistics for testing association between
phenotype and genotypes using a linear mixed model. By default, BOLT-LMM
assumes a Bayesian mixture-of-normals prior for the random effect attributed
to SNPs other than the one being tested. This model generalizes the standard
infinitesimal mixed model used by previous mixed model association methods,
providing an opportunity for increased power to detect associations while
controlling false positives. Additionally, BOLT-LMM applies algorithmic
advances to compute mixed model association statistics much faster than
eigendecomposition-based methods, both when using the Bayesian mixture model
and when specialized to standard mixed model association.
The BOLT-REML algorithm estimates heritability explained by genotyped SNPs and
genetic correlations among multiple traits measured on the same set of
individuals. BOLT-REML applies variance components analysis to perform these
tasks, supporting both multi-component modeling to partition SNP-heritability
and multi-trait modeling to estimate correlations. BOLT-REML applies a Monte
Carlo algorithm that is much faster than eigendecomposition-based methods for
variance components analysis at large sample sizes.

Alternatives

Package Version Architecture Repository
bolt-lmm - - -

Requires

Name Value
libboost iostreams1.67.0
libboost-program options1.67.0
libc6 >= 2.14
libgcc1 >= 1:3.0
libgfortran5 >= 8
libgomp1 >= 4.9
liblapack.so.3 -
liblapack3 -
libnlopt0 >= 2.2.4
libopenblas base
libstdc++6 >= 5.2
zlib1g >= 1:1.1.4

Download

Type URL
Binary Package bolt-lmm_2.3.2+dfsg-3+b1_amd64.deb
Source Package bolt-lmm

Install Howto

  1. Update the package index:
    # sudo apt-get update
  2. Install bolt-lmm deb package:
    # sudo apt-get install bolt-lmm

Files

Path
/usr/bin/bolt
/usr/share/doc/bolt-lmm/changelog.Debian.amd64.gz
/usr/share/doc/bolt-lmm/changelog.Debian.gz
/usr/share/doc/bolt-lmm/changelog.gz
/usr/share/doc/bolt-lmm/copyright
/usr/share/man/man1/bolt.1.gz

Changelog

2018-11-16 - Dylan Aïssi <daissi@debian.org>
bolt-lmm (2.3.2+dfsg-3) unstable; urgency=medium
* According to upstream, restrict arch to amd64 only. (Closes: #909858)
* Standards-Version: 4.2.1.
2018-06-07 - Dylan Aïssi <bob.dybian@gmail.com>
bolt-lmm (2.3.2+dfsg-2) unstable; urgency=medium
* Add libnlopt-cxx-dev to Build-Depends to fix FTBFS.
* Install example files in the correct folder.
2018-05-25 - Dylan Aïssi <bob.dybian@gmail.com>
bolt-lmm (2.3.2+dfsg-1) unstable; urgency=medium
* Initial release. (Closes: #899400)

See Also

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bomberclone-data_0.11.9-7.1_all.deb Data files for bomberclone game
bomberclone_0.11.9-7.1_amd64.deb free Bomberman clone
bomstrip_9-12_amd64.deb tool to strip Byte-Order Marks from UTF-8 text files
bonnie++_1.98_amd64.deb Hard drive benchmark suite
boohu_0.12.0-1_amd64.deb Break Out Of Hareka's Underground -- a roguelike game
bookletimposer_0.2-5_all.deb PDF imposition toolkit
boolector_1.5.118.6b56be4.121013-1+b1_amd64.deb SMT solver for bit-vectors and arrays
boolstuff-dev_0.1.16-1_amd64.deb library for operating on boolean expression binary trees - devel
boolstuff_0.1.16-1_amd64.deb programs for operating on boolean expression binary trees
boomaga_1.3.0-1_amd64.deb virtual printer for viewing a document before printing
boot-info-script_0.77-1_all.deb inspect boot environment
bootcd_5.14_all.deb run your system from cd without need for disks
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